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The 10 Best Organ Support Supplements

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Best Organ Support Supplements

What are the best organ support supplements?

While taking hormones to enhance your performance, you need to be mindful of protecting your organs, especially the liver that processes any substances you take.

That’s why organ support supplements are so important, as they deliver valuable nutrients to help protect your body from the potential side effects of bodybuilding supplements.

It’s great to take cycle support supplements throughout your whole cycle, but how do you choose the best ones to take with all the organ support supplements out there?

We’ve made it easy for you by putting together this list of the best organ support supplements.

So, before your next cycle, consider adding one of these top organ support supplements to your routine.

 

The Best Organ Supplements Compared

Our supplement lists are created by researching the best-reviewed products from the most reputable web sources.

Here’s our list of the 10 best organ support supplements:

 

In A Rush? Here’s Our Top Pick:

Best Organ Support Supplement Overall
Huge Nutrition Defend (30 Servings)
$49.95
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10. Prometheuz Suppz – Cycle Sustainer

Best Organ Support Supplement For Cholesterol
Prometheuz Suppz Cycle Sustainer (60 Servings)
$26.98 ($0.22 / Count)
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    12/01/2021 02:36 pm GMT

    If you’re looking for a cycle support supplement that helps maintain healthy cholesterol levels and promotes liver function, then Prometheuz Suppz – Cycle Sustainer is a great choice.

    You get 60 servings of two capsules each, offering 7.8mg of vitamin B6, 85mg of grape seed extract, 50mg of milk thistle, and 30mg of TUDCA.

    75mg of hawthorn antioxidants and 50mg of saw palmetto support prostate health and also help to reduce estrogen and boost testosterone.

    The brand says its TUDCA formula decreases metabolites in the liver to flush out toxins and support normal liver function.

    These supplements are gluten-free and made to GMP standards in a U.S. facility, so you can trust the quality.

    Pros

    • All-natural formula with effective ingredients.
    • Promotes healthy cholesterol levels.
    • Helps with healthy liver function.
    • 60 servings per container.
    • Gluten-free cycle supplement.
    • Made in U.S. GMP facility.

    Cons

    • Lower dosage compared to some brands.

     

    9. Rich Piana 5% Nutrition – Post Gear PCT

    Best Post Cycle Organ Support Supplement
    Rich Piana 5% Nutrition Post Gear PCT (30 Servings)
    $52.99 ($0.22 / Count)
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      12/01/2021 01:11 pm GMT

      Rich Piana 5% Nutrition – Post Gear PCT is ideal for coming off a cycle as it boosts testosterone levels to help maintain cycle gains.

      Each serving has 125mcg of vitamin D, 10.5mg of vitamin B6, and 20mg of vitamin E. There’s 30mg of zinc, 70mg of magnesium, and 24mg of calcium too.

      In addition to essential vitamins and minerals, the Post Gear PCT formula includes 3,120mg of D-aspartic acid and 300mg of longjack extract for a powerful testosterone complex.

      These supplements help balance hormones and build muscle while also blocking estrogen, thanks to natural aromatase inhibitors.

      The 1,150mg estrogen control complex includes proven ingredients like brassaiopsis glomerulata, DIM, stinging nettles, and acacetin.

      Pros

      • Post cycle therapy testosterone support.
      • Protects cycle gains with healthy hormone levels.
      • 3,120mg of D-aspartic acid.
      • Black pepper extract helps with absorption.
      • Good source of vitamin B, D, and E.
      • High in zinc.

      Cons

      • 8 capsules per serving.

       

      8. Purus Labs – Organ Shield

      Best Antioxidant Organ Support Supplement
      Purus Labs Organ Shield (30 Servings)
      $19.99
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      Purus Labs – Organ Shield is the best antioxidant cycle support supplement with coenzyme Q10.

      You get 60 gelatin capsules per container from a trusted supplement brand with 300mg of milk thistle extract and 250mg of soy extract.

      There’s also 200mg of saw palmetto and 150mg of alpha-lipoic acid in every serving.

      The brand says its innovative blend of antioxidants creates a plant-based complex to fight free radicals and ensure the vital organs are well-protected.

      You can take these cycle support supplements to promote healthy heart, liver, and prostate function while increasing energy production.

      Pros

      • High in antioxidants and coenzyme Q10.
      • Carefully designed to protect and restore.
      • Promotes cell growth and maintenance.
      • Improves energy production.
      • Great for detoxification.
      • Protects prostate.

      Cons

      • Gelatin capsules are not suitable for vegetarians or vegans.

       

      7. Reborn Labs – Cycle Protection

      Best Organ Support Supplement For Blood Pressure
      Reborn Labs Cycle Protection (30 Servings)
      $19.95 ($0.33 / Count)
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        12/01/2021 08:21 pm GMT

        Reborn Labs – Cycle Protection is the best organ support supplement for blood pressure and liver protection.

        With two veggie capsules per serving, you get 200mg of milk thistle, 50mg of beetroot, 30mg of zinc, and much more, not to mention the 512mg prop blend made of fruits and veggies.

        Artichoke extract, chicory root, celery seed, alfalfa, grape seed extract, turmeric, and ginger are also highly effective in this formula.

        All the natural botanical ingredients protect the heart and liver to help eliminate toxins and promote proper bodily functions throughout the cycle.

        These supplements are non-GMO and lab-tested, too, for peace of mind.

        Pros

        • 100% natural blood pressure support.
        • Veggie capsules with 22 ingredients.
        • Convenient two-capsule serving.
        • Fast-acting liver protection.
        • Comprehensive cycle support.
        • Non-GMO and lab-tested.

        Cons

        • Dosage isn’t as high as some supplements.

         

        6. Competitive Edge Labs –  Cycle Assist

        Best Value Organ Support Supplement
        Competitive Edge Labs Cycle Assist (30 Servings)
        $26.95 ($0.11 / Count)
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        12/02/2021 12:21 am GMT

        Competitive Edge Labs – Cycle Assist is the best value organ support supplement with 60 servings of all-in-one cycle support.

        You get advanced liver support and organ protection from 500mg of milk thistle, 450mg of hawthorn berry extract, and 160mg of saw palmetto berry extract.

        75mg of grape seed and celery seed extract plus 15mg of zinc also provide powerful support for your heart and liver.

        The brand says its formula contains on-cycle and post-cycle essentials to help control cholesterol and offset any negative side effects from the anabolic cycle.

        Four capsules a day give your body the support it needs to maximize the benefits of bodybuilding supplements.

        Pros

        • Great value with 60 nutrient-packed servings.
        • Carefully formulated to offset anabolic cycle side effects.
        • 500mg of milk thistle for antioxidant power.
        • 75mg of grape seed extract for heart health.
        • Good for on and post cycle.
        • Controls cholesterol.

        Cons

        • Not as many ingredients as other supplements.

         

        5. Rich Piana 5% Nutrition – Liver & Organ Defender

        Best Organ Support Supplement For Heart Health
        Rich Piana 5% Nutrition Liver & Organ Defender (30 Servings)
        $42.99
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        Rich Piana 5% Nutrition – Liver & Organ Defender is the best for heart health with a unique combo of milk thistle and L-glutathione.

        The all-in-one formula offers comprehensive support for liver, heart, prostate, and kidney support.

        It’s a liver-detoxifying supplement that’s high in antioxidants to reduce inflammation and keep the heart healthy, whether you’re just starting or finishing a cycle.

        Each serving offers 1,100mg of hawthorn berry extract powder, 600mg of milk thistle powder, and 400mg of alpha-lipoic acid, among many more nutrients.

        It also reduces acne and cholesterol to help you maintain a clear, healthy complexion, especially with zinc, selenium, garlic, dimagnesium maleate, and more.

        Pros

        • Liver and organ defender with 17 active ingredients.
        • Heart, kidney, and prostate support.
        • 1,100mg of hawthorn berry powder.
        • 600mg of milk thistle powder.
        • Reduces acne and cholesterol.
        • Effectively flushes out toxins.

        Cons

        • 9 capsules per serving.

         

        4. Nutriissa – Cycle Support

        Best Mega-Dosed Organ Support Supplement
        Nutriissa Cycle Support (30 Servings)
        $59.95 ($59.95 / Count)
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          12/01/2021 09:46 pm GMT

          Nutriissa – Cycle Support is the best mega-dosed organ support supplement for natural holistic healing.

          The 6,000mg dosage is ideal for liver and organ protection, and these supplements are also non-GMO, gluten-free, and vegan.

          Twenty-two active ingredients are working together to provide the highest level of organ support.

          This formula specializes in liver, heart, kidney, prostate, and skin support with the best vitamins and minerals.

          The brand says its cycle support supplements reduce oxidative stress, fight free radicals, and prevent illness and inflammation.

          The easy-to-swallow softgels are free of animal products, allergens, and harsh chemicals for reliable protection against harsh chemical enhancers.

          Pros

          • Mega-dosed supplement with 22 active ingredients.
          • 6,000mg dose for liver, kidney, and prostate health.
          • High amounts of vitamin B, D, & E.
          • No animal products or allergens.
          • Reduces oxidative stress.
          • Heart and skin support.

          Cons

          • 8 capsules per serving.

           

          3. Blackstone Labs – Gear Support

          Best Organ Support Supplement For Prostate Function
          Blackstone Labs Gear Support (45 Servings)
          $29.99
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          Blackstone Labs – Gear Support is an excellent organ support supplement for prostate function and heart health.

          Not only is it a great value with 90 capsules per bottle and only one or two capsules needed per day, but it’s also jam-packed with nutrients like red clover extract and N-acetyl cysteine.

          It supports liver, heart, and cardiovascular health while also giving your immune system a boost and protecting from free radical damage.

          Gear Support combats high blood pressure, too, as all the ingredients come together to purify the blood and flush out unwanted toxins.

          By ensuring natural body processes continue throughout the whole cycle, you can maximize muscle mass gains without sacrificing your health.

          Pros

          • Good bulk buy – 90 capsules per container.
          • Contains red clover and hawthorn berry extracts.
          • Supports healthy prostate and liver.
          • Purifies blood and flushes toxins.
          • Protects against free radicals.
          • Boosts immune system.

          Cons

          • Not quite as many ingredients as some other brands.

           

          2. Jacked Factory – Defend-XT

          Best Organ Support Supplement For Liver Protection
          Jacked Factory Defend XT (30 Servings)
          $24.99
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          Jacked Factory – Defend-XT is a top choice for liver and organ support, as it contains powerful antioxidants to promote organ health.

          It’s designed for bodybuilders, elite athletes, and fitness enthusiasts who can benefit from this advanced anti-inflammatory support formula.

          There is 500mg of milk thistle seed powder, 400mg of N-acetylcysteine, 150mg of Bergamot orange fruit, and 5mg of BioPerine black pepper fruit extract to help with normal liver function.

          The fruit extracts promote healthy blood pressure and reduce LDL cholesterol levels too.

          Just take two capsules once daily with food throughout your cycle to get a high level of organ protection without unnecessary fillers or dyes.

          Pros

          • Advanced cardiometabolic formula.
          • 500mg of milk thistle extract.
          • Great for liver and cardio support.
          • Only need to take two capsules once daily.
          • Reduces bad cholesterol levels.
          • Zero fillers or dyes.

          Cons

          • Need multiple bottles to cover most cycles.

           

          1. Huge Nutrition – Defend

          Best Organ Support Supplement Overall
          Huge Nutrition Defend (30 Servings)
          $49.95
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          Huge Nutrition – Defend is the best organ support supplement overall, thanks to a scientific formula of high-quality ingredients proven to support the organs.

          Each bottle contains 120 capsules, enough for 30 daily servings of four capsules with 1,000mg of milk thistle extract, 600mg of N-acetyl cysteine, and 500mg of peppermint leaf powder.

          You also get 250mg of saw palmetto extract and tauroursodeoxycholic acid, 150mg of hawthorn berry extract, and 200mg of red clover in each serving.

          These nutrients combine to provide powerful on-cycle and liver support for total organ protection while running a cycle.

          It’s best to take Defend from start to finish of your cycle to get all the benefits of this leading organ support supplement.

          Pros

          • Clinically dosed ingredients.
          • 1,000mg of milk thistle extract.
          • Combines healthy nutrients all in one formula.
          • Powerful on-cycle organ protection.
          • Maintains healthy lipid profile.
          • Made in the U.S. in FDA registered facility.
          • GMP manufacturing practices.

          Cons

          • Need to take four a day with one meal.

           

          FAQs About Organ Support Supplements

          Organ support supplements are an important part of your hormone cycle support, as they protect vital organs and help you stay healthy.

          For more information, check out our answers to the most frequently asked questions about organ support supplements.

           

          Q: What Is SARM Cycle Support?

          Selective androgen receptor modulators (SARMs) are performance-enhancing substances that initiate anabolism by increasing muscle mass and recovery.

          When on a SARM cycle, typically between 4-12 weeks, you can also take cycle support supplements to protect your organs from the potential side effects of extra hormones or steroids.

          Organ support supplements are important for protecting the liver, kidney, heart, and skin so you can get the most out of your cycle without compromising your overall health.

           

          Q: When Should I Take Organ Support Supplements?

          Organ support supplements should be taken alongside your cycle throughout the entire 4-12 weeks for the best results.

          By taking cycle support supplements, you give your body the best chance of success for your strength training cycle.

          These supplements are designed to protect your heart, kidney, and liver to ensure your organs stay healthy and strong while processing different substances.

           

          Q: What Supplements Should I Take on Gear?

          The best cycle support supplements to take on Gear include vitamin D, iron, caffeine, and creatine.

          That’s because all of these nutrients offer impressive protection to essential bodily functions and can offset possible side effects during your cycle.

          Acne and the increased risk of liver damage are just a few of the possibilities to be aware of when on cycle, so it makes sense to take organ support supplements just to be safe.

           

          Q: Does Milk Thistle Help with Steroids?

          Advanced cycle support supplements with milk thistle help offset the side effects of steroids, such as skin changes and weight gain.

          Milk thistle is an important part of these scientifically proven formulas, as it promotes liver health and helps flush out toxins from steroids.

          Sometimes steroids can disturb your mood and sleep too, which is why the all-in-one formula of the best organ support supplements makes a big difference by combining milk thistle with numerous other nutrients.

           

          Q: Which Organ Support Supplement to Choose?

          Choosing an organ support supplement for pre or post-cycle therapy depends on which nutrients you want the most, whether that be vitamin B, vitamin D, milk thistle, hawthorn berry extract, or zinc.

          Always check the ingredient list and see which areas cycle support supplements targets, such as heart, kidney, or skin health.

          Another consideration when selecting cycle support supplements is how many capsules you have to take per serving.

          Some brands with a higher dosage recommend 4-9 capsules per serving, while others need just one or two.

          Whichever supplements you choose, you can look forward to an effective nutrient formula that flushes out toxins and helps your organs perform properly throughout the entire cycle.

           

          Summary

          If you’re planning a bodybuilding hormone cycle anytime soon, make sure organ support supplements are also at the top of your list.

          These supplements are jam-packed with nutrients that support healthy liver and heart function, which helps you stay healthy while also boosting hormones and muscle strength.

          Ingredients like milk thistle extract and N-acetyl cysteine are part of antioxidant-rich cycle support supplements that can make a big difference to your overall health and training goals.

          Best Organ Support Supplement Overall
          Huge Nutrition Defend (30 Servings)
          $49.95
          Shop Huge Nutrition
          We earn a commission if you click this link and make a purchase at no additional cost to you.

          Here’s a quick recap of the 10 best organ support supplements:

          1. Huge Nutrition – Defend
          2. Jacked Factory – Defend-XT
          3. Blackstone Labs – Gear Support
          4. Nutriissa – Cycle Support
          5. Rich Piana 5% Nutrition – Liver & Organ Defender
          6. Competitive Edge Labs –  Cycle Assist
          7. Reborn Labs – Cycle Protection
          8. Purus Labs – Organ Shield
          9. Rich Piana 5% Nutrition – Post Gear PCT
          10. Prometheuz Suppz – Cycle Sustainer

          What’s your favorite organ support supplement? Leave a comment below. 

          With almost two decades of lifting experience under his belt, Matt shares his knowledge and expertise with us around bodybuilding and supplementation. Deadlifts and barbell curls are his go-to exercises, and, when he's not writing about health and fitness, you'll find him in the gym busting out some arms! Follow Jacked Gorilla on Instagram: @jackedgorillanews

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