Which are the best Cissus supplements?
Cissus quadrangularis, or Devil’s Backbone as it’s more commonly known, is a perennial plant of the grape family.
It has been used by African, Indian, and Thai cultures as traditional medicine for centuries.
The plant is believed to possess potent antioxidant compounds and anti-inflammatory properties that offer various health benefits, ranging from healing broken bones to reducing high cholesterol.
Cissus quadrangularis is also thought to help support fat loss and promote lean muscle development when combined with regular exercise.
In this article, we’ve researched and compared all of the Cissus quadrangularis supplements on the market and rounded up the very best.
Here are the 10 best Cissus supplements:
Top 10 Cissus Supplements Compared
Our supplement lists are created by researching the best-reviewed products from the most reputable companies and web sources.
10. Keter Wellness – Cissus Pro 1000
Cissus Pro 1000 by Keter Wellness is designed to promote healthy bone structure and joint function.
Each bottle contains 120 capsules, or 60 servings, all providing you with 1,000mg of Cissus Quadrangluaris Stem Extract.
Other ingredients include Hypromellose and L-Leucine.
The brand suggests that supplementing with Cissus may help strengthen bones, ligaments, and tendons, build healthy muscle mass, and support optimum weight management.
The supplement is manufactured in the USA in a certified GMP facility and is 100% free from fillers, additives, artificial colors, and flavors.
Keter Wellness recommends taking two capsules twice a day, approximately 30 minutes before a meal, with a glass of water for best results.
9. Bronson – Cissus Quadrangularis
Bronson Cissus Quadrangularis capsules are formulated to help maintain healthy cortisol levels and support joint function.
Each bottle contains 120 capsules, or 60 servings, all providing you with 1,000mg of Cissus Quadrangularis Stem Extract.
Other ingredients include microcrystalline cellulose, magnesium stearate, and silicon dioxide.
Bronson suggests that taking Cissus may promote healthy joints and mobility, support strong bones, connective tissue, and overall joint health.
The supplement is Non-GMO, free from gluten and soy, and manufactured in the USA in the brand’s state-of-the-art cGMP registered facility.
Bronson recommends adults take two capsules a day with a meal for best results.
8. VitaMonk – Cissus Quadrangularis
VitaMonk’s Cissus Quadrangularis helps promote healthy joints and glucose levels.
Each bottle comes with 120 capsules, providing you with 60 servings all containing 1,000mg of Cissus Quadrangularis (Aerial Extract).
Other ingredients include rice flour and hypromellose.
Vitamonk suggests that taking Cissus regularly may help rebuild cartilage, reduce cortisol, and optimize hormones such as testosterone.
They also state that it may help improve glucose response in healthy individuals and even reduce body fat and boost lean muscle mass.
The supplement is free from dairy, metallic colorants, eggs, stearates, high fructose corn syrup, artificial preservatives, BPA, gluten, and banned substances.
Vitamonk recommends taking two capsules a day for best results.
7. InnovaPharm – Superior Cissus
Superior Cissus by InnovaPharm, is designed to support joint and cartilage health.
Each bottle contains 180 capsules, providing you with 30 servings, all containing 4,800mg of Cissus Quadrangularis.
InnovaPharm suggests that Cissus can promote a healthy inflammatory response and help support bones, joints, and connective tissue.
The supplement is free from wheat, gluten, soy, fish, shellfish, eggs, milk, and tree nuts but is produced in a GMP-compliant facitilty that processes other ingredients containing these allergens.
Other ingredients include gelatin, magnesium stearate, rice flour, and silicon dioxide.
6. BulkSupplements – Cissus Quadrangularis
BulkSupplements Cissus powder helps support healthy ligaments, tendons, and cartilage.
Each pouch contains 1,000 servings, providing you with approximately 500mg of Cissus Quadrangularis Extract per serving.
The supplement does not contain any other ingredients and is 100% free from added sugar, soy, dairy, gluten, and additives.
Aside from supporting healthy bones, the brand suggests that Cissus Quadrangularis extract may also help with weight management and fortified the immune system.
They also state that it may help reduce swelling and irritations in the body and help maintain healthy cholesterol levels and support the cardiovascular system.
BulkSupplements recommends taking one serving once or twice daily for best results.
5. NatureBell – Cissus Extract
NatureBell’s Cissus Quadrangularis Extract is formulated to support joint health, tendon tissue, cartilage, and bone.
Each bottle contains 180 capsules, or 90 servings, all providing you with 1,000mg of pure Cissus Quadrangularis Extract.
Other ingredients include silicon dioxide, magnesium stearate, rice flour, and gelatin.
The brand suggests that using Cissus may also help promote muscle recovery and antioxidant support for the immune system.
The supplement is Non-GMO, free from soy, gluten, and dairy, and is manufactured and third-party tested in the USA.
NatureBell recommends adults take two capsules daily, ideally with meals, for best results.
4. Absonutrix – Cissus
Absonutrix Cissus capsules are designed to help support overall joint health.
Each bottle contains 120 capsules, or 60 servings, all providing you with 1,600mg of Cissus Quadrangluaris.
Other inactive ingredients include gelatin, corn starch, and magnesium stearate.
The supplement is made in the USA and does not contain shellfish, glucosamine, chondroitin, or MSM.
Absonutrix recommends taking two capsules a day with breakfast and dinner for best results.
3. Primaforce – Cissus
Primaforce Cissus capsules are formulated to promote optimal joint health.
Each bottle contains 120 capsules, or 60 servings, all providing you with 1,000mg of Cissus Quadrangularis.
Other ingredients include cellulose, magnesium stearate, and silicon dioxide.
Primaforce suggests that Cissus may also be helpful for weight management by suppressing appetite, stimulating metabolism, and burning fat.
They also state that it can also strengthen your immune system, improve respiratory conditions, and help calm general aches and pains.
Primaforce recommends consuming one serving twice a day, approximately 30 minutes before meals, for best results.
2. Toniiq – Cissus Quadrangularis
Toniiqs Cissus Quadrangularis is formulated to support joint function and immune health.
Each tub contains 120 capsules, or 60 servings, all containing 1,200mg of Cissus Quadrangularis extract.
Other ingredients include hydroxypropyl methylcellulose, vegetable cellulose, vegetable magnesium stearate, and silicon dioxide.
The brand suggests that just one of their capsules is the equivalent of one hundred raw Cissus quadrangularis powder capsules.
The supplement is produced in a GMP-certified and NSF-approved state-of-the-art manufacturing facility in Miami, USA, and is free from artificial preservatives, wheat, and gluten.
Toniiq recommends taking two capsules a day for best results.
1. Double Wood Supplements – Cissus Extract
Double Wood Supplements Cissus Extract is designed to promote healthy cortisol levels and bone and joint health.
Each bottle contains 150 capsules, or 75 servings, all providing you with 1,000mg of Cissus Quadrangularis Extract.
Other ingredients include hypromellose, cellulose, and rice flour.
The brand suggests that using Cissus may also boost creatine levels, support and promote pain-free joints, and rebuild cartilage and damaged fibers.
The supplement is made in the USA, and third-party tested to ensure purity and potency.
Double Wood Supplements recommends taking two capsules a day to support bone and joint health.
Frequently Asked Questions About Cissus Supplements
Q: What Is Cissus Quadrangularis?
Cissus Quadrangularis, also known as veldt grape, or devil’s backbone, is a perennial plant from the grape family.
It’s native to Asia, Arabia, and certain regions of Africa and has been used as traditional medicine in African and Ayurvedic cultures for thousands of years.
Cissus Quadrangularis is believed to provide various health benefits and is a popular supplement for bone health and joint support.
Today, most herbal supplements use extracts produced from their leaves, roots, and stems.
Q: What Are The Benefits of Cissus?
Cissus Quadrangularis is most commonly used to heal broken bones, injured ligaments, tendons, and weight loss.
It’s also used to treat conditions like high cholesterol, hemorrhoids, gout, asthma, and diabetes, as well as a range of other ailments, aches, and pains in the human body.
Cissus Quadrangularis is believed to contain high levels of vitamin C, antioxidant compounds like carotenoids, tannins, and phenols, analgesic, and anti-inflammatory properties that offer a variety of medicinal properties.
It’s also believed that this powerful plant may provide support against chronic conditions like heart disease, osteoporosis, and strokes.
Q: Does Cissus Have Any Side Effects?
Cissus Quadrangularis can be used safely for six to 12 weeks when taken according to the manufacturer’s recommend serving guidelines.
However, in some people, Cissus quadrangularis may cause side effects like headaches, diarrhea, stomach discomfort, gas, dry mouth, and insomnia.
Due to the limited research and understanding on the safety of taking Cissus quadrangularis during pregnancy, it’s best to air on the side of caution and avoid taking this supplement while pregnant or breastfeeding.
Cissus quadrangularis may also lower blood sugar, which may lower levels too much if taken with medications for diabetes. Hence, it’s best to check with your doctor or healthcare provider before use.
Q: How Do I Take Cissus Supplements?
At the time of writing, there is no official recommend dosage for Cissus quadrangularis.
However, all of the supplements featured in this roundup provide daily recommended doses ranging between 500 to 4,800mg.
Cissus quadrangularis supplements come as powder, capsules, syrup, and softgels, with the most popular being capsules.
After consulting with your doctor or healthcare provider, you should start using your chosen supplement by taking a lower dose than the manufacturer recommends.
From there, you can slowly work your way up to the recommended daily serving size once you’ve assessed your tolerance.
Q: Which Cissus Supplement Should I Choose?
All the supplements featured in this roundup are manufactured and produced by well-known supplement brands.
As a rule of thumb, we suggest choosing a Cissus quadrangularis supplement that clearly lists all ingredients on their Supplement Facts label and uses as many natural ingredients as possible.
Supplements that have been certified by these organizations are more likely to contain the exact ingredients and amounts listed on the product label.
We hope you enjoyed our list of the 10 best Cissus supplements.
Hopefully, you now know everything you need to know about Cissus quadrangularis.
If you’d like to learn more about other beneficial supplements, check out our latest guides.
Here’s a quick recap of the 10 best Cissus supplements:
- Double Wood Supplements – Cissus Extract
- Toniiq – Cissus Quadrangularis
- Primaforce – Cissus
- Absonutrix – Cissus
- NatureBell – Cissus Extract
- BulkSupplements – Cissus Quadrangularis
- InnovaPharm – Superior Cissus
- VitaMonk – Cissus Quadrangularis
- Bronson – Cissus Quadrangularis
- Keter Wellness – Cissus Pro 1000