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Annihilate Review



This is our Annihilate review by Huge Nutrition.

Annihilate is a laxogenin based supplement developed by Huge Nutrition. Laxogenin is a chemical found in plants that helps to stimulate plant growth. Whilst the research for its use in bodybuilding and sport is still limited, many people in the industry have put it to the test.

Huge Nutrition is one of the many brands that have decided to capitalize on the growing popularity of laxogenin, releasing their product Annihilate.

In this review, we’re going to be talking about Annihilate, the ingredients, price, and effectiveness.


Annihilate Review

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Annihilate Laxogenin Supplement (60 Servings)

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After checking out Annihilate ourselves, we want to discuss the following in this review:

  • Important information
  • Servings/bottle size
  • Suggested stacks
  • Ingredients
  • Laxogenin overview
  • Price
  • Where to buy
  • Effectiveness
  • Frequently asked questions


Important Information

Before we get into the big stuff like the ingredients, prices, flavors, and effectiveness; let’s quickly cover some important information on servings, product weight, and potential supplement stacks.


Bottle Size/Serving Count

A single bottle of Annihilate contains 60 capsules, and Huge Nutrition recommends taking 1-2 capsules per day, resulting in either a 30 serving or 60 serving bottle depending on your preference.


Suggested Stacks

Insanity Stack (Annihilate, Arachidone & Epitech)

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Huge Nutrition recommends stacking Annihilate with some of their other muscle-building products such as Arachidone (Arachidonic acid) and Epitech (Epicatechin).


Annihilate Ingredients/Supplement Facts

Annihilate Review

Since Annihilate is a laxogenin supplement, it contains just one ingredient.

Here’s a full breakdown of Annihilate’s ingredients and dosages:


5a-Hydroxy Laxogenin – 100mg

5a-hydroxy laxogenin, otherwise known as 5 alpha-hydroxy laxogenin or Laxosterone, is a synthetic derivative of laxogenin.

Laxogenin is produced from the plant steroid diosgenin, which is actually used as a raw material for over 50% of synthetic steroids. Laxogenin helps to promote plant growth.

Most laxogenin marketed supplements will contain 5a-hydroxy laxogenin.

The compound has become rather popular for use in bodybuilding during recent years, with many positive reviews.

However, its research for such a purpose is still limited, and it’s not currently approved by the FDA for official medical use.

Whilst we’re unable to say conclusively that laxogenin is effective for the purpose most athletes use it, it’s often thought to help with the following:

  • Increasing protein synthesis
  • Building muscle
  • Burning fat
  • Lowering cortisol levels

Laxogenin is not a prohormone or steroid and is approved for use as a dietary supplement.

What we can say is that people seem to love it, and if you’re going to try a laxogenin supplement for yourself, Huge Nutrition uses the official compound. Most companies only include an extract, often in the form of Similax Sieboldii.

100mg is the common dosage used in dietary supplements.



Top Pick
Annihilate Laxogenin Supplement (60 Servings)

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We earn a commission if you click this link and make a purchase at no additional cost to you.

Now we’ve covered all the important information about the product itself, let’s talk about the cost.

The price of Annihilate from Huge Nutrition is $59.95 for a 60 capsule bottle. They often offer 10% discount codes on their website, so be sure to check out if you can get a small discount when purchasing.

As for the value, $50-$60 is an accurate price for a high-quality laxogenin supplement.

Where can you buy Annihilate?

You can buy Annihilate direct on the Huge Supplements website. 



As we’ve already mentioned, the research and studies on this compound are still very limited, and it’s not approved for medical use. Laxogenin is approved as a dietary supplement, and a large number of consumers have praised its ability to help aid performance in the gym.

The effectiveness of taking a laxogenin supplement may also be reliant on genetics, and some may experience different effects from others. Whilst I have experienced gains whilst taking a laxogenin supplement, it wasn’t always the only supplement I was taking, and it was very difficult to gauge just how beneficial it was for me personally.

However, the majority of customers who have purchased, tested, and reviewed Huge Nutrition’s Annihilate have seen steady gains in their lifts and their overall strength.

The supplement has a 4.5-star rating on the Huge Supplements website, and it’s one of their best-selling products. All other information aside, that should speak for itself, and considering Huge Nutrition is a well-trusted brand using both ‘clinically effective’ ingredients and dosages, we can’t see any reason not to recommend trying it out for yourself.


Frequently Asked Questions

This section is dedicated to covering some of the most common questions people have when it comes to Annihilate.


Q: How Can I Use Annihilate?

Annihilate is a great natural muscle-building supplement. The key ingredient in this product is 5a-Hydroxy Laxogenin, known as the plant steroid. This natural plant anabolic will help you with increasing lean muscle mass, strength, and performance. It is safe to use by both males and females.


Q: How Do I Take Annihilate?

The recommended dosage is 1 to 2 capsules per day taken in the morning with a meal. Huge Nutrition advises running it for at least 8 weeks to see optimal results.


Q: Can I Stack This Product?

Yes, it is actually advised to do so in order to optimize results. You can stack this product with any other Huge Nutrition supplement. Huge Nutrition advises stacking it with Arachidone (Arachidonic Acid) and Epitech (Epicatechin).


Q: How Long Should I Use Annihilate?

It is advised to run Annihilate for at least 8 weeks with a maximum of 12 weeks. 



So where does Annihilate stack up as a laxogenin supplement?

In our personal opinion, if you’re going to try out laxogenin as a dietary supplement for yourself, Annihilate is a very good option. They use the core compound instead of an extract, and the dosage is the recommended dosage as per online discussions and industry talk.

You can buy a bottle of Annihilate on the Huge Supplements website, and we highly recommend you check out some of their other best-selling products.

We’ve currently reviewed the following Huge Nutrition supplements:

What do you think about this Annihilate review? Leave a comment below.

Dan Western is the owner of Jacked Gorilla. Dan has 8+ years of experience in the fitness industry and has been researching supplement usage for the same period of time. Over the years, he's logged thousands of hours of research, tried and tested hundreds of different supplements, and also experimented with his own formulas. Right now he's working on launching his own supplement company. Follow Jacked Gorilla on Instagram: @jackedgorillanews

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